Resolution of Vitamin A in Dropping Melanoma Hazard:
Promising
findings on reducing melanoma risk have come from a new study that has found
that one of the benefits of vitamin a supplements might be to offer protection
against disfiguring, dangerous and sometimes deadly melanoma. Despite this,
researchers are not suggesting you start taking vitamin A supplements, as this
nutrient can be dangerous in high doses.
Vitamin
A is found naturally in foods like carrots, eggs, milk, liver, spinach and
sweet potatoes and plays a key role in our vision, bone health, reproduction,
cell division and differentiation as well as helping to manage the immune
system.
It's
also known to help the skin cancer and mucous membranes stay strong and keep out both
bacteria and viruses. Surveys have found that most Americans get enough vitamin
A in the diet, and deficiencies in this country are rare.
The
researchers looking for a link between vitamin A and melanoma examined melanoma
risk for 69,635 subjects who were 62 years old on average. After a period of
six years, 566 had been diagnosed with melanoma.
For
the 59,000 subjects who had never taken vitamin A supplements there were 506
melanomas, but for the 5,800 who were taking supplements and had used them
regularly over the past decade, there were just 28 cases.
In
fact, those who got additional vitamin A through supplements had almost a 40%
less chance to be diagnosed with melanoma as those who didn't take such
supplements.
The
strange thing is, it was only the supplements that lowered the risk, not
getting the nutrient from foods.
The
reduced risk was more significant in women compared to men, and the protection
was greatest in parts of the body that have frequent exposure to the rays of
the sun. Women may benefit more than men because they are more susceptible to
skin damage from UV radiation than men are.
The
researchers are emphatic that the reduction in melanoma was associated with the
supplements not the nutrient obtained from the diet. They know this because the
protective benefits were only seen in those who were taking on board more
vitamin A than can be found in commercially available multivitamin formulas.
And
it was only the vitamin A, not arytenoids that brought the lower risk of
melanoma. A carotenoid is a precursor (converted by the body as needed) to
vitamin A - beta-carotene or lycopene may be names you know.
Other
experts, not involved in the work, aren't surprised that vitamin A offers some
protection against melanoma. The thing is, experts are quick to warn that the
findings are preliminary and that excessive amounts vitamin A is a dangerous
thing; it can bring serious risks such as birth defects, lower bone mineral
density or liver toxicity, as well as troublesome symptoms like dry skin or
hair loss.
The
National Institutes of Health recommends a daily intake of 700 micrograms of
vitamin A for women and 900 micrograms for men. Taking over 2,800 micrograms
can lead to toxic symptoms.
Researchers
speculate that supplements of this nutrient might have a place in high risk
patients such as those who are fair skinned, have a history of sunburn or a lot
of moles on their skin. For the rest of us, if you're concerned about skin
cancer, be smart about the sun and supplement with a multivitamin that has the
benefits of vitamin A as one of many nutrients. These people should also avoid
the sun, use sun protection consistently and have an annual skin exam by a
dermatologist.
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